(2S)-2-acetamido-2-(4-fluorophenyl)acetic acid
N-ACETYL-2-(4-FLUOROPHENYL)-L-GLYCINE
CAS: 136815-01-5
Molecular Formula: C10H10FNO3
(2S)-2-acetamido-2-(4-fluorophenyl)acetic acid - Names and Identifiers
| Name | N-ACETYL-2-(4-FLUOROPHENYL)-L-GLYCINE |
| Synonyms | N-Ac-S-4-Fluorophenylglycine N-ACETYL-2-(4-FLUOROPHENYL)-L-GLYCINE (S)-2-AcetaMido-2-(4-fluorophenyl)acetic acid (2S)-2-acetamido-2-(4-fluorophenyl)acetic acid Benzeneacetic acid, α-(acetylamino)-4-fluoro-, (S)- (9CI) |
| CAS | 136815-01-5 |
| InChI | InChI=1/C10H10FNO3/c1-6(13)12-9(10(14)15)7-2-4-8(11)5-3-7/h2-5,9H,1H3,(H,12,13)(H,14,15)/t9-/m0/s1 |
(2S)-2-acetamido-2-(4-fluorophenyl)acetic acid - Physico-chemical Properties
| Molecular Formula | C10H10FNO3 |
| Molar Mass | 211.19 |
| Density | 1.313±0.06 g/cm3(Predicted) |
| Boling Point | 439.2±40.0 °C(Predicted) |
| Flash Point | 219.4°C |
| Vapor Presure | 1.72E-08mmHg at 25°C |
| pKa | 3.14±0.10(Predicted) |
| Refractive Index | 1.537 |
(2S)-2-acetamido-2-(4-fluorophenyl)acetic acid - Introduction
(S)-N-acetyl-p-fluorophenylglycine (N-Acetyl-L-phenylalanine) is an organic compound. It is an amino acid derivative formed by acylation of the side chain carboxyl group of phenylalanine (phenylalanine) with acetic acid.
(S)-N-acetyl-p-fluorophenylglycine is a chiral compound and has optical activity. Its physical properties include:
-Molecular formula: C13H15NO3F
-Molecular weight: 259.26g/mol
-Appearance: White solid
-Melting point: 152-156°C
In chemical and biochemical research,(S)-N-acetyl-p-fluorophenylglycine is commonly used as a chiral reagent and synthetic intermediate. It can be used to synthesize drugs, hormones, cosmetics and other bioactive molecules. In addition, it can also be used as a synthetic intermediate for optical materials, pigments and catalysts.
The method for preparing (S)-N-acetyl-p-fluorophenylglycine includes reacting phenylalanine with acetic anhydride, and performing an acylation reaction under alkaline conditions.
With regard to safety information, laboratory safety procedures need to be strictly followed. This compound may be irritating to the human body and should be avoided by inhalation, contact with skin and ingestion. During operation, appropriate personal protective equipment, such as laboratory gloves and protective glasses, should be worn. In case of any doubt or accident, a doctor or professional should be called immediately.
(S)-N-acetyl-p-fluorophenylglycine is a chiral compound and has optical activity. Its physical properties include:
-Molecular formula: C13H15NO3F
-Molecular weight: 259.26g/mol
-Appearance: White solid
-Melting point: 152-156°C
In chemical and biochemical research,(S)-N-acetyl-p-fluorophenylglycine is commonly used as a chiral reagent and synthetic intermediate. It can be used to synthesize drugs, hormones, cosmetics and other bioactive molecules. In addition, it can also be used as a synthetic intermediate for optical materials, pigments and catalysts.
The method for preparing (S)-N-acetyl-p-fluorophenylglycine includes reacting phenylalanine with acetic anhydride, and performing an acylation reaction under alkaline conditions.
With regard to safety information, laboratory safety procedures need to be strictly followed. This compound may be irritating to the human body and should be avoided by inhalation, contact with skin and ingestion. During operation, appropriate personal protective equipment, such as laboratory gloves and protective glasses, should be worn. In case of any doubt or accident, a doctor or professional should be called immediately.
Last Update：2024-04-09 20:52:54
